NICE breast cancer guideline

Figure depicting cancer of the breast in NICE Orange

An easy-to-read NICE guidance summary on the classification and care of people at risk of familial breast cancer or with a family history of breast cancer.

Breast cancer is the most commonly diagnosed cancer in the UK: one in five people with a breast cancer diagnosis have a family history of the disease. Multiple factors contribute to development of breast cancer – lifestyle, environmental, hormonal and genetic. Inherited genetic mutations account for 5% of all breast cancers. As it is common, a family history of breast cancer does not necessarily predispose to hereditary breast cancer. Factors associated with inherited breast cancer include early age of onset, bilateral disease and a family history of other malignancies.

This Guidelines for Nurses summary provides recommendations for assessing carrier probability, determining when to refer, breast cancer screening and surveillance, and risk-reducing options. It includes an algorithm to help determine whether to offer genetic testing or specialist referral to people concerned about their risk of breast cancer.

Please register to continue reading this content

Register for free

Guidelines for Nurses is completely free for UK-based doctors, nurses, and pharmacists