NICE breast cancer guideline

Figure depicting cancer of the breast in NICE Orange

An easy-to-read NICE guidance summary on the classification and care of people at risk of familial breast cancer or with a family history of breast cancer.

Breast cancer is the most commonly diagnosed cancer in the UK: one in five people with a breast cancer diagnosis have a family history of the disease. Multiple factors contribute to development of breast cancer – lifestyle, environmental, hormonal and genetic. Inherited genetic mutations account for 5% of all breast cancers. As it is common, a family history of breast cancer does not necessarily predispose to hereditary breast cancer. Factors associated with inherited breast cancer include early age of onset, bilateral disease and a family history of other malignancies.

This Guidelines for Nurses summary provides recommendations for assessing carrier probability, determining when to refer, breast cancer screening and surveillance, and risk-reducing options. It includes an algorithm to help determine whether to offer genetic testing or specialist referral to people concerned about their risk of breast cancer.

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